In this presentation, Michael Ellyot and Matt Hector-Taylor, co-founders of IoT Ventures, discuss developing an end to end solution (device-network-customer application) that delivers real value to end users and can scale throws up many challenges. These include dynamic management of devices, sensing and activation, networks and coverage, noise reduction (front and back ends). Using various solutions developed in APAC for animal, people, asset, environment and agricultural monitoring as reference examples, we will discuss these challenges and approaches to overcome them.